PTK2B and Alzheimer disease: In 2013, a meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for AD (HLA-DRB5–HLA-DRB1, PTK2B, SORL1, SLC24A4-RIN3, DSG2, ZCWPW1, CELF1, FERMT2, NME8, CASS4, MEF2C) [25].