Genes upregulated by SOX9 expression in HUVECs overlapped with genes upregulated in fibroblasts versus endothelial cells in atherosclerotic lesions, while genes downregulated by SOX9 expression in HUVECs were enriched in endothelial cells versus fibroblasts in atherosclerotic lesions (Supplementary Figure S2D and S2E). Here, SOX9 is linked to Atherosclerotic lesion.