Genes and proteins regulating the TCA cycle (PDHA1, SUCLG2, SUCLG1, and IDH2) as well as mitochondrial function (VDAC1, MRPS31, LARS2, OPA1, and MTIF2) showed higher transcripts and protein levels in Wnt‐high compared with Wnt‐low tumor entities (Fig 6B). The gene discussed is VDAC1; the disease is neoplasm.