Heterozygous mutations in MORC2 gene have been associated with a spectrum of disorders affecting the peripheral nervous system such as Charcot‐Marie‐Tooth (CMT2Z), spinal muscular atrophy‐like with or without cerebellar involvement, and a developmental syndrome associated with impaired growth, craniofacial dysmorphism and axonal neuropathy (DIGFAN syndrome). This evidence concerns the gene MORC2 and axonal neuropathy.