We hypothesized that conjugation of CTX-M13 φ with either the NIR II IR1050 dye (Figure 1A, left panel, schematic) or SWCNT (Figure 1B, left panel, schematic) to the p8 coat proteins of M13 φ would allow detection of CTX-M13 φ at the site of patient-derived GBM22 brain tumors in an intracranial orthotopic xenograft murine model of GBM using SWIR imaging. This evidence concerns the gene GOLPH3 and brain neoplasm.