The DEMs targeting DYRK2 were miR-181a-5p, miR-326, and miR-874-3p (positively correlated to islet autoantibodies) and miR-148b-3p, all previously related to T1D and/or autoimmune diseases [1, 2, 17, 21, 22]. The gene discussed is DYRK2; the disease is type 1 diabetes mellitus.