The GPR12 protein expressions in low-grade serous ovarian cancer (LGSOC), high-grade serous ovarian cancer (HGSOC), mucinous adenocarcinoma (MC), endometrioid adenocarcinoma (EC), clear cell adenocarcinoma (CCA), and normal ovarian epithelial tissues were examined by immunohistochemical staining, respectively. The gene discussed is GPR12; the disease is ovarian serous adenocarcinoma.