KL and chronic kidney disease: The recent publications with higher citation bursts were coming from Hu et al. (29), Leifheit-Nestler et al. (30), and David et al. (31); Hu et al. and Leifheit-Nestler et al. demonstrated that LVH in CKD may be attributed to a deficiency of soluble klotho, thus, implying a potential therapeutic strategy in uremic cardiomyopathy.