Interestingly, the JAK2 p. V617F mutation has not been identified in ALL and only a single JAK2 exon 14 mutation, JAK2 p. L611S, has been reported in an ALL setting (Kratz et al., 2006; Funakoshi-Tago et al., 2009; Gnanasambandan and Sayeski, 2011; Jain et al., 2017; Konoplev et al., 2017). This evidence concerns the gene JAK2 and acute lymphoblastic leukemia.