Ai et al. found that Dubosiella was significantly reduced in high-fat diet mice, and rice bran fermented with Lactobacillus fermentum MF423 could significantly increase the abundance of Dubosiella and improve insulin resistance (57), they also found that Dubosiella was positively correlated with HDL, GSH-Px and SOD, and negatively correlated with TC and LDL. The gene discussed is SOD1; the disease is Insulin resistance.