The risk of hospitalization with COVID-19 was associated with the genes small ribosomal protein S6 (RPS6) and a member of the SWI/SNF family involved in ATP-dependent chromatin remodeling complexes (SMARCA5) identified by Schneider et al. (2021) and RuthHanna et al. (2021), respectively. The gene discussed is SMARCA5; the disease is COVID-19.