In addition, we also found enrichment of sex-related signals such as GO_REGULATION_OF_GONAD_DEVELOPMENT (adjusted p = 0.023), endometriosis (adjusted p = 7.3 × 10−4), sex hormone-binding globulin levels (adjusted p = 0.003), and sex hormone levels (adjusted p = 0.024; Supplementary Table S8). The gene discussed is PLXNA3; the disease is endometriosis.