Lysosomal acid lipase deficiency (LAL-D) is an autosomal recessive lysosomal storage disorder, caused by homozygous or compound heterozygous disease-causing variants in the LIPA gene located on chromosome 10q23.2 (Pisciotta et al., 2017; Wilson and Patni, 2020). Here, LIPA is linked to lysosomal acid lipase deficiency.