Xu et al. (2020) pointed out that as a molecular sponge for miR-155, HOXA11-AS was significantly upregulated in HSCC and exerted a pro-tumorigenic effect by sponging a tumor suppressor miR-155 in HSCC. Our results indicated that SM was able to inhibit the development of FaDU xenograft tumors through suppression of HOXA11-AS, also providing evidence for HOXA11-AS on tumor regulation. The gene discussed is HOXA11; the disease is neoplasm.