GJB2 and neoplasm: Furthermore, XFZYD decreased the expression of c-FOS and increased the mRNA levels of rpr, hid, and grim in the RasV12/lgl−/− background, indicating that XFZYD may hinder tumour cell invasion by suppressing JNK/AP-1 signalling and promoting tumour cell apoptosis by activating caspase signalling.