Furthermore, β-elemene regulates the expression of several key molecules involved in tumor angiogenesis and metastasis, including vascular endothelial growth factor (VEGF), matrix metalloproteinases (MMPs), E-cadherin, N-cadherin, and vimentin, playing a regulatory role in the invasion and metastasis of a variety of tumor cells [20–25]. Here, VIM is linked to neoplasm.