To ulteriorly identify the silencing efficiency of COPS3 siRNA, we detected the expression of COPS3 in tumor tissues of mice via IHC and immunoblot assays, and the data revealed that compared with the negative groups, the protein levels of COPS3 were efficiently restrained by COPS3 siRNA in the COPS3 depletion groups (Figures 6(b) and 6(c)). This evidence concerns the gene COPS3 and neoplasm.