described other significant differences in 10-year DFS in pediatric patients with PPGL, including the presence of metastatic disease (29.6% vs. 43.5% in those without metastatic disease, p = 0.014), and PGL (36.6% vs. 47.8% in PCC, p = 0.039), whereas the presence of an SDHB mutation was associated with lower DFS but did not reach statistical significance (45.1% in non- SDHB vs. 24.4% in SDHB, p = 0.063) (7). The gene discussed is SDHB; the disease is metastatic neoplasm.