Furthermore, Model II, which adjusted for age, sex, ethnicity, SBP, DBP, RR, heart rate, GCS, diabetes, sepsis, renal failure, chronic pulmonary disease, vasopressor, embolization of aneurysm, clipping of aneurysm, WBC, platelet, hemoglobin, glucose, BUN and creatinine, the higher serum AG still remained significantly associated with an increase in ICU (HR: 2.31 [95% CI: 1.58–3.38]) and hospital all-cause mortality (HR: 1.91 [95% CI: 1.36–2.67]) with the low serum AG group as reference. The gene discussed is RENBP; the disease is acute kidney injury.