To further decipher the potential contribution(s) of Smn, Tweak, and Fn14 depletion to SMA muscle pathology, we used commercially available mouse myopathy and myogenesis qPCR arrays (SABiosciences), which measure expression levels of a subset of 84 genes known to display and/or regulate myopathy and myogenesis. This evidence concerns the gene SMN2 and myopathy.