Moreover, based on the public database, GEPIA (http://gepia.cancer-pku.cn/), CKAP5 was up-regulated in BRCA (breast invasive carcinoma) tissues relative to normal breast tissues, whereas SRSF7 was not differentially expressed in BRCA tissues and normal tissues (Fig. 3B). This evidence concerns the gene SRSF7 and invasive breast carcinoma.