IFNG and melanoma: To identify the conservation of the IFNγ response, we analyzed RNA-seq of additional murine solid tumors treated with IFNγ, including B16F10 (melanoma) and MC38 (colon adenocarcinoma), which revealed concordant transcriptional responses (Additional file 1: Fig. S1A, B) across all cell types (Additional file 1: Fig. S1C).