ATG2B and Ewing sarcoma: In our study, ATG2B, ATG10 and DAPK1 were strictly screened as the final potential protective ARGs by univariate and multivariate Cox regression, LASSO (Fig. 1A, B), KM analysis (Figs. 1C, 2A–C), pathway map analysis (Fig. 2D) and PPI network analysis (Fig. 2E) for the prognostic model of ES.