Besides, we used BISAP score instead of APACH-II score to analyze the severity of pancreatitis because some test results needed in the APACH-II score system were not available, and research had confirmed that BISAP is as useful as APACHE-II and more effective than Ranson criteria, CTSI, CRP, HCT and BMI in predicting severity, organ failure, and death in patients with acute pancreatitis25. The gene discussed is CRP; the disease is pancreatitis.