LYVE1 and prostate intraepithelial neoplasia: To gain more in-depth insight into transcriptomic changes in hARtg regulated prostatic oncogenesis, we performed bulk RNA-sequencing (RNA-seq) analyses using RNA samples isolated from microscopically confirmed PIN or PCa tissues with more than 80% atypical or tumor cells, respectively, from R26mTmG/hAR:Osr1Cre/+ mice, as well as prostate tissues from sex and age-matched WT mice.