TGFB1 and non-small cell lung carcinoma: Considering the fact that many NSCLC cell lines are resistant to TGF-β-induced growth inhibition [50], it would be particularly interesting to systematically investigate whether RGS6 can help to restore response of NSCLC cells to TGF-β-induced growth inhibition or apoptosis and whether the ability of RGS6 to induce growth inhibition and apoptosis contributes to its function in suppressing TGF-β-induced metastases in vivo.