Although this study does not report any biological function of the upregulated RGS6 transcripts in these ovarian cancer cells, and there is no evidence indicating that RGS6 may exhibit either pro- or anti-tumor actions depending on cancer types, these differential expression profiles of RGS6 in different types of cancer cells render thorough investigations to elucidate the molecular mechanisms underlying the tumor-suppressing function of RGS6 necessary for application of RGS6 in development of new anti-cancer therapy. The gene discussed is RGS6; the disease is cancer.