HLA-G and neoplasm: However, contrasting data have been reported regarding the role of tumor cell HLA-G expression in the CRC setting (Fukushima et al. 1998; Guo et al. 2015; Kaprio et al. 2021; Reimers et al. 2014; Swets et al. 2016; Ye et al. 2007; Zeestraten et al. 2013; Zhang et al. 2017).