ELOVL4 and psoriasis: This identified a single nucleotide polymorphism (SNP), rs62407622, located within the ELOVL4 gene that was associated with a strong reduction in ELOVL4, both in primary keratinocytes (P < 2.0 × 10–16, Figure 14B) and lesional psoriasis skin (P = 2.1 × 10–2, Supplemental Figure 14).