Furthermore, multicolor fluorescence immunohistochemistry has revealed that the positive rate of cells co‐expressed with NOTCH3 and SMARCA4 was markedly higher in the MUC5AC and MUC2 co‐overexpression positive group and that there was a higher positive correlation between NOTCH3 and SMARCA4 in CRC patients with the co‐overexpression of MUC5AC and MUC2 (Fig. 7). The gene discussed is SMARCA4; the disease is colorectal carcinoma.