The expression of Enpp1, Slc20a2, Ank, Bglap, Pdpn, Runx2, Bmp2, Npnt, and Tnfrsf11b was decreased, whereas femoral expression of Fgf23, and Adipoq, was increased in CKD mice when compared to control mice (Fig. 1A). This evidence concerns the gene BGLAP and chronic kidney disease.