They identified HLA-B*44:03 and HLA-DQB1*04:02 as potential risk factors for dipyrone-related SJS/TEN with SOC in the Brazilian population of European ancestry, and HLA-C*05:01 as a potential risk factor for dipyrone-related SJS/TEN with SOC in the Pardo Brazilian population (Wakamatsu et al., 2021). This evidence concerns the gene HLA-B and toxic epidermal necrolysis.