IKZF1 and toxic epidermal necrolysis: We found that a meta-analysis using samples from Japanese, Korean, Indian, and Brazilian patients revealed a significant genome-wide association between CM-related SJS/TEN with SOC and IKZF1 [rs4917014 (G vs. T), OR = 0.5, p = 8.5 × 10–11] (Ueta et al., 2015a).