We have suspected that a common function of CMs such as acetaminophen and dipyrone is highly implicated in the onset of SJS/TEN with SOC (Ueta et al., 2010a; Ueta, 2016; Ueta, 2018; Ueta, 2020; Ueta, 2021a; Ueta, 2021b). Here, UBXN11 is linked to toxic epidermal necrolysis.