NFE2L2 and alkaline phosphatase measurement: Studies have shown that Nrf2 regulates the physiological function of mitochondria, DNA damage repair, and inflammatory reactions (Tebay et al., 2015; Ahmed et al., 2017; Mohan and Gupta, 2018), which are involved in the development of many inflammatory diseases, including AP (Keleku-Lukwete et al., 2018).