Recently, Louisa and others supported the potential benefits of Moringa oleifera in cardiovascular or metabolic disorders, mainly by ameliorating the undesired pro-inflammatory response and inhibiting oxidative stress by mediating molecular mechanisms such as hindering nuclear factor kappa B (NF-κB) translocation or enhancing the antioxidant response of nuclear factor-erythroid factor 2-related factor 2 (Nrf2) in different preclinical models (Louisa et al., 2022). The gene discussed is NFE2L2; the disease is metabolic disease.