TNF and Hyperglycemia: Although there was limited information on its cardioprotective effects, much evidence suggests Moringa oleifera extracts can significantly decrease pro-inflammatory and apoptotic markers such as TNF-α, IL-1β, IL-6, NF-κβ, caspase 3, caspase 9, and tumor protein (p53) to alleviate the detrimental effects of hyperglycemia in preclinical models of T1D (Muhammad et al., 2016; Omodanisi et al., 2017a; Azevedo et al., 2018; Oguntibeju, 2019).