In this study, we also investigated the correlations between 35 polymorphisms in 9 DNA repair genes (XRCC3, BRCA2/ZAR1L, XPC, RAD52, MAD2L2, NFKB1, NFKBIA, TNFRSF1A, and FASN) with platinum-based chemotherapy prognosis in 399 patients with lung cancer. The gene discussed is MAD2L2; the disease is lung cancer.