Enterococcus gallinarum, which is translocated to the liver from the intestine induced by disrupted intestinal barrier in AIH, encodes shikimic acid pathway, produces Ah R ligand, and activates AhR-CYP1A1 signaling pathway, ultimately promoting the transcription of CYP1A1 (Manfredo Vieira et al., 2018). The gene discussed is CYP1A1; the disease is autoimmune hepatitis.