FBN1 and polycystic ovary syndrome: Asprosin is reported to downregulate mTOR expression, which inhibits follicular activation in PCOS (Wang and Hu, 2021; Zhang et al., 2022), while exercise decreases asprosin level and improves mTOR concentration (Ko et al., 2019; Stepto et al., 2020), so it is speculated that asprosin might play a role in alleviating PCOS with exercise.