By searching the expression of GPX2 in lung adenocarcinoma in GEPIA 2 database and matching with TCGA normal data, it revealed that GPX2 expression levels were significantly higher in lung adenocarcinoma tissues than in normal tissues, and there was a highly significant difference in GPX2 expression levels between the two groups of samples (P < 0.01). The gene discussed is GPX2; the disease is lung adenocarcinoma.