Given that immune checkpoints play a crucial role in tumor immunosuppression, we analyzed the correlation between NCAPG2 expression and that of the immune checkpoint-related genes CD274, CTLA4, HAVCR2, LAG3, PDCD1, PDCD1LG2, TIGIT, and SIGLEC15 in LGG using Pearson’s correlation analysis. This evidence concerns the gene SIGLEC15 and neoplasm.