The neuroactive ligand receptor interaction, calcium signaling pathway, jak stat signaling pathway, extracellular matrix (ECM) receptor interaction, pathways in cancer, Wnt signaling pathway, mammalian target of rapamycin (mTOR) signaling pathway, basal cell carcinoma, melanogenesis, and cytokine-cytokine receptor interaction gene sets were significantly enriched in the high SETBP1 expression group. The gene discussed is SETBP1; the disease is cancer.