However, it has recently been determined that NADPH-cytochrome P450 reductase (POR) favors the induction of ferroptosis due to the cytoplasmic production of H2O2 (69), which is inhibited by Fer-1 or by the intracellular expression of catalase (69) but thus far, this finding is limited to cervical cancer cells (HeLa). The gene discussed is POR; the disease is cervical carcinoma.