Placental parasitemia and intervillositis were associated with increased LC3II protein levels and autophagosomes/lysosomes in the placenta (induced autophagy); however, reduced Rab7 and unaltered SQSTM1/p62 levels supported autophagy blockage with consequent impaired degradation of autophagosome content (89). Here, SQSTM1 is linked to parasitic infectious disease.