In addition, the expression of major immune checkpoint targets, such as PD1, TIGIT, and TIM-3, was significantly elevated in the high-CRRS group (Figures 7I–M), and CRRS had a negative association with the recognition of cancer cells by T cells (Figure 7G), further suggesting an immune-suppressive characterization of the high-CRRS group. This evidence concerns the gene PDCD1 and cancer.