Nucleotide metabolism, primary immunodeficiency, pyrimidine metabolism, and retinol metabolism were significantly enriched in the high BTN3A2 subgroup, whereas aldosterone-regulated sodium reabsorption, and HIF-1 signaling pathway, nitrogen metabolism, and renal cell carcinoma were significantly enriched in the low BTN3A2 subgroup (Supplementary Figure 3A). Here, BTN3A2 is linked to renal cell carcinoma.