We then compared the JMJD8 expression between altered and non-altered pathways on UALCAN and noticed that JMJD8 was elevated in altered SWI/SNF complex, p53/Rb-related pathway, and chromatin modifiers status in HNSC and GBM while poorly expressed in BRCA (Figure 6B). The gene discussed is RB1; the disease is glioblastoma.