We then analyzed the JMJD8 mRNA level differences between pan-cancer and corresponding normal tissues on TIMER2.0; JMJD8 mRNA was significantly upregulated in 11 cancer types (BRCA, CHOL, COAD, ESCA, GBM, HNSC, KIRP, LIHC, LUAD, PRAD, and STAD) and downregulated in CESC, KICH, KIRC, and THCA (Figure 2B). This evidence concerns the gene JMJD8 and cancer.