Spatial transcriptional data on SpatialDB were obtained to depict the spatial overlapping of JMJD8 and M2 macrophage biomarkers CD68 and CD163 on BRCA and PRCA cancer tissues (Figure 8C), and as expected, JMJD8, CD68, and CD163 markers presented similar spatial distributions, which implied potential co-expression of JMJD8, CD68, and CD163. This evidence concerns the gene CD163 and cancer.