INS and type 2 diabetes mellitus: Among the 49 patients with T2D, 42 were treated with blood glucose-lowering agents: 2 were treated with sulfonylureas alone, 8 with metformin alone, 6 were on sulfonylurea + metformin, 7 were on insulin alone, 1 patient was on a combination of sulfonylurea + insulin, 11 were on metformin + insulin, 4 were on a combination of sulfonylurea + metformin + insulin, 2 were on metformin + incretin agonists, and 1 patient was on combination of metformin + insulin + incretin agonist (20).