Non-hematologic grade 3 adverse events were reported to beinfection/neutropenic fever in 61% (18/28), hypophosphatemia in 29% (8/28),hyperglycemia/hyperbilirubinemia/increased AST or ALT in 11% (3/28),pneumonitis/acute kidney injury/hypokalemia/vomiting in 7% (2/28) of patients. The gene discussed is GPT; the disease is Hyperglycemia.