DM and its concurrent chronic inflammatory processes lead to tumor progression, epithelial‐mesenchymal transition (EMT), and metastasis by the production of inflammatory cytokines (interleukin 6 (IL‐6) and tumor necrosis factor-alpha (TNFα)), and leading to the activation of kinases p38 MAPK and nuclear factor kappa B (NFкB) [35]. Here, TNF is linked to neoplasm.