In another study, increased blood urea nitrogen, elevated LDH, elevated NLR, elevated CRP, decreased albumin, and decreased natremia, which then led to the creation of a laboratory risk score for the early prediction of COVID-19 severity and in-hospital mortality, with a satisfying ability for the early prediction of both severity (AUC = 0.95) and mortality (AUC = 0.84), although this study's limitations include the retrospective single-center nature which may limit the generalizability of the findings and the short follow-up period comprehended in the report [18]. The gene discussed is CRP; the disease is COVID-19.