First, the program initializes age (30–95) and the four different diet types (“HFO_diet,” “Starvation,” “HL_diet,” “CR”) along with the factors that are related to prodromal or mixed AD (ATP, MFN1, MFN2, DRP1, FIS1, Diabetes, Oxidative_Stress, Hypertension, Obesity, Depression, and Physical_activity). Here, ATP8A2 is linked to depressive disorder.