In our study, CSF IL-6 did not correlate with CSF AD biomarkers (Spearman’s rho = 0.053, p = 0.4 for Aβ42; Spearman’s rho = −0.014, p = 0.829 for p-tau; and Spearman’s rho = −0.05, p = 0.427 for Aβ42/p-tau). This evidence concerns the gene MAPT and Alzheimer disease.